|Di haynṭtsayṭiḳe proleṭarishe Yidishe dikhṭung in Ameriḳe - Kurland, David|
|Glibenclamide for the Treatment of Acute CNS Injury. (Volume 6) - Kurland, David B.|
This article is from Pharmaceuticals, volume 6.AbstractFirst introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic KATP [sulfonylurea receptor 1 (Sur1)-Kir6.2] channels. During the last decade, glibenclamide has received renewed attention due to its pleiotropic protective effects in acute CNS injury...
|The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity. (Volume 3) - Tosun, Cigdem|
This article is from Brain Sciences, volume 3.AbstractWe studied a model of hemorrhagic encephalopathy of prematurity (EP) that closely recapitulates findings in humans with hemorrhagic EP. This model involves tandem insults of 20 min intrauterine ischemia (IUI) plus an episode of elevated venous pressure induced by intraperitoneal glycerol on post-natal day (P) 0. We examined Sur1 expression, which is upregulated after focal ischemia but has not been studied after brief global ischemia includin...